The mnemonic
The three Ds
What each word stands for
- DermatitisPhotosensitive rash, Casal necklace
- DiarrhoeaGastrointestinal mucosal involvement
- DementiaNeuropsychiatric features
Why it matters clinically
Untreated niacin deficiency adds a fourth D, death. Suspect it in maize-based diets and Hartnup disease.
Where it stops being reliable
It does not capture the cause (niacin or tryptophan deficiency), only the presentation.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.