The mnemonic
Medullary, Phaeo, Parathyroid
What each word stands for
- MedullaryMedullary carcinoma of the thyroid
- PhaeoPhaeochromocytoma
- ParathyroidParathyroid hyperplasia causing hyperparathyroidism
- RETCausative proto-oncogene mutation
Why it matters clinically
Guides screening of relatives and the need to exclude phaeochromocytoma before thyroid surgery.
Where it stops being reliable
Does not cover MEN 1 (3 Ps) or MEN 2B (mucosal neuromas, marfanoid habitus), which differ.
Teaching aid, still awaiting independent review. Confirm facts in a standard source.