Gastrointestinal surgery: pseudomyxoma peritonei: practice question

A General Surgery question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Surgery · Gastrointestinal surgery: pseudomyxoma peritonei

Sample item

A woman has progressive abdominal distension with jelly-like mucinous ascites and a mucinous lesion of the appendix. What is the recommended treatment for fit patients?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy

Pseudomyxoma peritonei arises mostly from low-grade mucinous appendiceal neoplasm with peritoneal mucin spread. Cytoreductive surgery (peritonectomy) with HIPEC (Sugarbaker approach) gives the best control.

Option by option

  • A. Systemic radiotherapy

    Radiotherapy has no established role.

  • B. Simple appendicectomy only

    Appendicectomy alone leaves peritoneal disease untreated.

  • C. Repeated paracentesis alone

    Paracentesis is ineffective as mucin is viscous and recurs.

  • D. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (correct)

    Correct. CRS plus HIPEC is standard.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this General Surgery question

What is the answer to this General Surgery question?

The best answer is D, Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Pseudomyxoma peritonei arises mostly from low-grade mucinous appendiceal neoplasm with peritoneal mucin spread.

Why is "Systemic radiotherapy" not the answer?

Radiotherapy has no established role.

Why is "Simple appendicectomy only" not the answer?

Appendicectomy alone leaves peritoneal disease untreated.

Why is "Repeated paracentesis alone" not the answer?

Paracentesis is ineffective as mucin is viscous and recurs.

What concept does this question test?

It tests Gastrointestinal surgery: pseudomyxoma peritonei in General Surgery. Cytoreductive surgery (peritonectomy) with HIPEC (Sugarbaker approach) gives the best control.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal surgery: pseudomyxoma peritonei?

Learn classic signs and eponyms alongside what they diagnose. Then use the flashcards and the other General Surgery questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.