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General Surgery · Breast and endocrine surgery: DCIS management
Sample itemScreening mammography shows pleomorphic microcalcification, and biopsy shows high-grade comedo-type DCIS in a 2 cm area. What is the standard management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Wide local excision with whole-breast radiotherapy, with no axillary dissection
DCIS is non-invasive and is treated with excision to clear margins plus radiotherapy, or mastectomy for extensive disease. Nodal disease is not expected, so sentinel biopsy is considered only with mastectomy. Endocrine therapy may reduce recurrence if ER positive.
Option by option
A. Observation alone
Untreated high-grade DCIS may progress.
B. Axillary clearance with chemotherapy
Axillary clearance and chemotherapy are not needed.
C. Tamoxifen alone
Tamoxifen alone is inadequate local treatment.
D. Wide local excision with whole-breast radiotherapy, with no axillary dissection (correct)
Correct. Excision plus radiotherapy is standard.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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