Urology: Peyronie disease: practice question

A General Surgery question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Surgery · Urology: Peyronie disease

Sample item

A 55-year-old has painful erections with a new penile curvature and a palpable dorsal plaque for 6 months. Which agent is licensed for stable disease?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Intralesional collagenase clostridium histolyticum

Peyronie disease results from fibrous plaque formation in the tunica albuginea. Collagenase injection with modelling reduces curvature in the stable phase, and surgery (plication or grafting) is considered after about 12 months of stability.

Option by option

  • A. Radical penectomy

    Penectomy is not indicated.

  • B. Oral steroids

    Steroids are not effective.

  • C. Intralesional collagenase clostridium histolyticum (correct)

    Correct. Collagenase is used in stable plaque disease.

  • D. Testosterone injections

    Testosterone does not treat plaque.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More General Surgery questions

Questions about this General Surgery question

What is the answer to this General Surgery question?

The best answer is C, Intralesional collagenase clostridium histolyticum. Peyronie disease results from fibrous plaque formation in the tunica albuginea.

Why is "Radical penectomy" not the answer?

Penectomy is not indicated.

Why is "Oral steroids" not the answer?

Steroids are not effective.

Why is "Testosterone injections" not the answer?

Testosterone does not treat plaque.

What concept does this question test?

It tests Urology: Peyronie disease in General Surgery. Collagenase injection with modelling reduces curvature in the stable phase, and surgery (plication or grafting) is considered after about 12 months of stability.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Urology: Peyronie disease?

Learn classic signs and eponyms alongside what they diagnose. Then use the flashcards and the other General Surgery questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.