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General Surgery · Perioperative care: Frey syndrome after parotidectomy
Sample itemAfter superficial parotidectomy, a patient sweats and flushes over the cheek while eating. What is this and what is its mechanism?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Frey syndrome from aberrant regeneration of auriculotemporal parasympathetic fibres to sweat glands
Frey (gustatory sweating) syndrome follows damage to the auriculotemporal nerve, whose parasympathetic secretomotor fibres regrow to cutaneous sweat glands. Diagnosis is confirmed by the Minor starch-iodine test and treatment with botulinum toxin. The facial nerve is preserved at parotidectomy by identifying the trunk.
Option by option
A. First bite syndrome
First bite syndrome is pain at the first bite after parapharyngeal surgery.
B. Horner syndrome
Horner syndrome has ptosis and miosis.
C. Facial nerve palsy
Facial palsy causes weakness, not sweating.
D. Frey syndrome from aberrant regeneration of auriculotemporal parasympathetic fibres to sweat glands (correct)
Correct. Aberrant parasympathetic regeneration causes it.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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