Glycogen storage: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Glycogen storage

Sample item

Exercise intolerance with myoglobinuria from muscle glycogen phosphorylase deficiency is what disease?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. McArdle disease

This item reviews Glycogen storage; McArdle disease is the best answer because it directly fits the mechanism or morphology described.

Option by option

  • A. McArdle disease (correct)

    Correct. McArdle disease is supported by the defining finding.

  • B. Pompe disease

    Pompe disease does not match the key mechanism or pattern.

  • C. Wilson disease

    Wilson disease is not supported by the stated finding.

  • D. Hurler syndrome

    Hurler syndrome is plausible but is not the best fit here.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is A, McArdle disease. This item reviews Glycogen storage; McArdle disease is the best answer because it directly fits the mechanism or morphology described.

Why is "Pompe disease" not the answer?

Pompe disease does not match the key mechanism or pattern.

Why is "Wilson disease" not the answer?

Wilson disease is not supported by the stated finding.

Why is "Hurler syndrome" not the answer?

Hurler syndrome is plausible but is not the best fit here.

What concept does this question test?

It tests Glycogen storage in Biochemistry. The correct option holds because: Correct. McArdle disease is supported by the defining finding.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Glycogen storage?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.