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Anaesthesia · Thoracic anaesthesia: hypoxaemia during one-lung ventilation
Sample itemDuring one-lung ventilation for lobectomy, the saturation falls to 85%. What is the best immediate step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Give 100% oxygen and check the position of the double-lumen tube with a fibreoptic bronchoscope
The commonest cause of hypoxaemia is tube malposition, so FiO2 is raised to 1.0 and the position is confirmed bronchoscopically. Further measures include CPAP to the non-dependent lung, PEEP to the dependent lung, recruitment and, if needed, resuming two-lung ventilation. Large tidal volumes cause barotrauma and increase pulmonary vascular resistance.
Option by option
A. Switch to nitrous oxide for maintenance
Nitrous oxide lowers the available inspired oxygen concentration.
B. Increase the tidal volume to 15 mL/kg
A very large tidal volume risks lung injury and does not fix shunt.
C. Give 100% oxygen and check the position of the double-lumen tube with a fibreoptic bronchoscope (correct)
Correct. Tube position and oxygen concentration are checked first.
D. Apply PEEP to the non-ventilated lung only
CPAP, not PEEP, is the intervention to the non-dependent lung, and it comes after checking position.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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