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Anaesthesia · Special anaesthesia: thyroid storm
Sample itemA patient develops fever of 40 degrees C, heart rate of 160 per minute and agitation a few hours after thyroidectomy. Which drug controls the adrenergic features?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intravenous esmolol
This picture suggests thyroid storm. Beta blockade with esmolol or propranolol controls tachycardia, and propranolol also reduces peripheral T4 to T3 conversion. Treatment also includes a thionamide, iodine given after it, steroids, cooling and fluids; aspirin is avoided because it displaces thyroid hormone from binding proteins.
Option by option
A. Aspirin for the fever
Aspirin raises free thyroid hormone by displacing it from protein binding.
B. Intravenous esmolol (correct)
Correct. A beta blocker controls the adrenergic effects of thyroid hormone excess.
C. Neostigmine
Neostigmine causes bradycardia and secretions but does not treat thyroid storm.
D. Dobutamine
Dobutamine would worsen tachycardia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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