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Anaesthesia · Paediatric anaesthesia: oxygen consumption in neonates
Sample itemWhy do neonates desaturate faster than adults during apnoea?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Higher oxygen consumption per kilogram with a low functional residual capacity
Neonatal oxygen consumption is roughly 6 to 8 mL/kg/min compared with 3 to 4 mL/kg/min in adults, while functional residual capacity per kilogram is similar or smaller because of compliant chest walls and early airway closure. This leaves little oxygen reserve. Preoxygenation gives a short safe apnoea time, so intubation attempts must be brief.
Option by option
A. Lower oxygen consumption
Consumption is higher, not lower, in neonates.
B. Higher haemoglobin affinity for oxygen that releases it quickly
Fetal haemoglobin has higher affinity and releases oxygen less readily, which does not explain rapid desaturation.
C. A larger functional residual capacity
The functional residual capacity is not larger in relation to oxygen demand.
D. Higher oxygen consumption per kilogram with a low functional residual capacity (correct)
Correct. High consumption with little reserve leads to rapid desaturation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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