Obstetric anaesthesia: carboprost in asthma: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Obstetric anaesthesia: carboprost in asthma

Sample item

A woman with asthma has atonic postpartum haemorrhage unresponsive to oxytocin. Which uterotonic is contraindicated?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Carboprost

Carboprost (15-methyl prostaglandin F2 alpha) can cause bronchospasm and raise pulmonary vascular resistance, so it is contraindicated in asthma. Misoprostol and further oxytocin are acceptable second-line choices. Ergometrine is avoided in hypertension and pre-eclampsia.

Option by option

  • A. Misoprostol

    Misoprostol is not associated with bronchospasm and can be used.

  • B. Oxytocin infusion

    Oxytocin can be continued as an infusion.

  • C. Carboprost (correct)

    Correct. Carboprost causes bronchoconstriction and is avoided in asthma.

  • D. Tranexamic acid

    Tranexamic acid is an antifibrinolytic that is part of haemorrhage management.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is C, Carboprost. Carboprost (15-methyl prostaglandin F2 alpha) can cause bronchospasm and raise pulmonary vascular resistance, so it is contraindicated in asthma.

Why is "Misoprostol" not the answer?

Misoprostol is not associated with bronchospasm and can be used.

Why is "Oxytocin infusion" not the answer?

Oxytocin can be continued as an infusion.

Why is "Tranexamic acid" not the answer?

Tranexamic acid is an antifibrinolytic that is part of haemorrhage management.

What concept does this question test?

It tests Obstetric anaesthesia: carboprost in asthma in Anaesthesia. Misoprostol and further oxytocin are acceptable second-line choices. Ergometrine is avoided in hypertension and pre-eclampsia.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Obstetric anaesthesia: carboprost in asthma?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.