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Anaesthesia · Pain: ketorolac contraindications
Sample itemWhich patient should not receive ketorolac for postoperative analgesia?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. A patient with an eGFR of 25 mL/min and a history of peptic ulcer disease
Ketorolac is a potent non-selective NSAID. It is contraindicated in renal impairment, active or previous peptic ulcer or gastrointestinal bleeding, bleeding risk, and aspirin-sensitive asthma, and its use is limited to about 5 days. Renal and gastric protection depends on prostaglandins that it inhibits.
Option by option
A. A healthy adult after dental extraction
A healthy adult can receive a short course for dental pain.
B. A patient with an eGFR of 25 mL/min and a history of peptic ulcer disease (correct)
Correct. Renal impairment and peptic ulcer history are both contraindications.
C. A healthy adult after knee arthroscopy
A healthy adult can usually receive a short course.
D. A patient with osteoarthritis and normal renal function
Normal renal function and no other contraindication allow short-term use.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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