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Anaesthesia · Critical care: thromboelastography interpretation
Sample itemOn thromboelastography, a prolonged reaction (R) time suggests deficiency of which component?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Coagulation factors
The R time reflects the time to initial clot formation and depends on clotting factors, so prolongation is treated with plasma. Reduced maximum amplitude (MA) suggests platelet or fibrinogen deficiency, and reduced alpha angle points to fibrinogen. Increased lysis at 30 minutes indicates hyperfibrinolysis.
Option by option
A. Fibrinogen alone
Fibrinogen mainly affects the alpha angle and MA.
B. Platelets
Platelet function affects the maximum amplitude.
C. Coagulation factors (correct)
Correct. R time reflects clotting factor activity.
D. Fibrinolysis
Fibrinolysis shows as increased clot lysis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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