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Anatomy · Neuroanatomy: ascending tracts
Sample itemSecond-order neurons of the dorsal column-medial lemniscus pathway arise in the gracile and cuneate nuclei. A small medullary lesion interrupts their crossing to the opposite side. At which site, and in what form, do these fibres cross?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Lower medulla, as internal arcuate fibres
Dorsal column first-order axons ascend ipsilaterally in the gracile and cuneate fasciculi and synapse in the nuclei gracilis and cuneatus. Second-order axons sweep ventromedially as internal arcuate fibres, decussate in the lower medulla, and ascend as the medial lemniscus to the ventral posterolateral nucleus of the thalamus.
Option by option
A. Pons, as the trapezoid body
The trapezoid body carries crossing auditory fibres.
B. Spinal cord at the level of entry, as the anterior white commissure
The anterior white commissure is where spinothalamic fibres cross, not the dorsal column.
C. Thalamus, as the posterior commissure
The posterior commissure links pretectal and midbrain areas and is unrelated to this tract.
D. Lower medulla, as internal arcuate fibres (correct)
Correct. Crossing occurs in the lower medulla as internal arcuate fibres.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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