Try it
Anatomy · Neuroanatomy: cerebellum
Sample itemA child with a midline cerebellar medulloblastoma has truncal ataxia and cannot sit without support, while limb coordination is relatively preserved. Which deep cerebellar nucleus receives output from the vermis and is most affected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Fastigial nucleus
From lateral to medial, the deep nuclei are dentate, emboliform, globose and fastigial. The vermis projects to the fastigial nucleus, the most medial, which influences axial and proximal muscles through vestibulospinal and reticulospinal tracts; lesions give truncal ataxia. The lateral hemisphere projects to the dentate, causing limb dysmetria and intention tremor.
Option by option
A. Fastigial nucleus (correct)
Correct. The fastigial nucleus serves the vermis and controls truncal balance.
B. Emboliform nucleus
The emboliform nucleus belongs to the interposed pair for the paravermis and distal limb control.
C. Globose nucleus
The globose nucleus is also interposed, serving the paravermal region and limb tone.
D. Dentate nucleus
The dentate nucleus is lateral and receives the lateral hemisphere, giving limb ataxia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Anatomy questions
- Neuroanatomy: cerebellumA right cerebellar hemisphere stroke produces limb ataxia on which side?
- Neuroanatomy: cerebellumA lesion of the right cerebellar hemisphere most likely causes which sign?
- Upper limbA 24-year-old man falls on his shoulder and fractures the surgical neck of the humerus.…
- LarynxWhich intrinsic muscle of the larynx is the only abductor of the vocal cords?