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Anatomy · Neuroanatomy: language areas
Sample itemAfter a stroke, a right-handed man speaks fluently with normal grammar and understands commands, but cannot repeat the sentence he has just heard and substitutes wrong words. Which structure is most likely damaged?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Arcuate fasciculus connecting Wernicke and Broca areas
The arcuate fasciculus links the receptive Wernicke area with the expressive Broca area. Its lesion gives conduction aphasia, with fluent speech, good comprehension and poor repetition. Broca lesions cause non-fluent speech and Wernicke lesions cause fluent but meaningless speech with poor comprehension.
Option by option
A. Broca area in the inferior frontal gyrus
Broca area damage causes effortful, non-fluent speech with preserved comprehension.
B. Arcuate fasciculus connecting Wernicke and Broca areas (correct)
Correct. Disconnection of the two language areas impairs repetition alone.
C. Wernicke area in the superior temporal gyrus
Wernicke area damage causes impaired comprehension, which is normal here.
D. Primary auditory cortex in the transverse temporal gyrus
Primary auditory cortex damage would not selectively impair repetition and fluency.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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