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Dentistry · Oral histology and anatomy: interglobular dentine
Sample itemA child with vitamin D-resistant rickets has teeth in which histology reveals large unmineralised areas between calcospherites in the dentine. What is this finding called?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Interglobular dentine
Interglobular dentine arises when mineralisation fails to fuse calcospherites, as in vitamin D deficiency or excess fluoride. The tubules continue through these areas.
Option by option
A. Interglobular dentine (correct)
Correct. Failure of calcospherite fusion produces interglobular spaces.
B. Tomes granular layer
Tomes granular layer is a small zone beneath cementum in the root.
C. Dead tracts
Dead tracts are tubules emptied of odontoblast processes, usually from wear or caries.
D. Sclerotic dentine
Sclerotic dentine is tubule obliteration by mineral, not failed mineralisation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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