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Dentistry · Oral medicine and oral cancer: xerostomia treatment
Sample itemA 65-year-old with dry mouth following head and neck radiotherapy has difficulty swallowing and many new cavities. Which drug can be used to stimulate residual salivary function?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Pilocarpine
Pilocarpine is a muscarinic agonist that stimulates salivary secretion in patients with residual gland function after radiotherapy or Sjogren syndrome. Fluoride and saliva substitutes also help prevent caries.
Option by option
A. Pseudoephedrine
Pseudoephedrine causes dryness as a side effect.
B. Pilocarpine (correct)
Correct. Pilocarpine stimulates the remaining glandular tissue.
C. Amitriptyline
Amitriptyline has anticholinergic effects that reduce saliva.
D. Atropine
Atropine blocks muscarinic receptors and worsens dryness.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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