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Dentistry · Orthodontics: Down syndrome oral features
Sample itemA 12-year-old with Down syndrome has a large fissured tongue, delayed eruption and severe gingival destruction around lower incisors despite little plaque. What explains the periodontal state?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Impaired neutrophil chemotaxis and immune dysfunction
Patients with Down syndrome have early severe periodontitis out of proportion to plaque, due to defective neutrophil function and altered immunity. Other oral signs include macroglossia, hypodontia and delayed eruption.
Option by option
A. High calcium intake
High calcium intake has no role.
B. Impaired neutrophil chemotaxis and immune dysfunction (correct)
Correct. Immune defects drive the periodontal destruction.
C. Overgrowth of the mandible
The mandible is usually relatively small, not overgrown.
D. Excess salivary flow
Salivary flow is not excessive.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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