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Microbiology · Virology: hantavirus
Sample itemA young man cleans a long-closed, rodent-infested grain shed and 10 days later develops fever, myalgia and then rapidly progressive breathlessness with non-cardiogenic pulmonary oedema, haemoconcentration and thrombocytopenia. What is the most likely mode of acquisition?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Inhalation of aerosolised rodent excreta
Hantavirus pulmonary syndrome is caused by hantaviruses such as Sin Nombre virus, which is carried by rodents and shed in urine, droppings and saliva. Humans are infected by inhaling aerosols from contaminated areas, and person-to-person spread is rare. Treatment is supportive, with early intensive care.
Option by option
A. Sexual contact
Sexual transmission does not occur.
B. Inhalation of aerosolised rodent excreta (correct)
Correct. Aerosolised rodent excreta in enclosed spaces is the typical source.
C. A mosquito bite
Hantaviruses are not mosquito-borne.
D. A tick bite
Ticks are not vectors of hantavirus.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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