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Microbiology · Parasitology: liver flukes
Sample itemA man from southern China who regularly eats raw freshwater fish has recurrent cholangitis, and 20 years later develops cholangiocarcinoma. Stool shows small, operculated eggs with prominent shoulders. Which parasite is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Clonorchis sinensis
Clonorchis sinensis, the Chinese liver fluke, is acquired by eating raw or undercooked freshwater fish that carry metacercariae, and lives in the bile ducts. Chronic infection predisposes to cholangiocarcinoma. Praziquantel is the treatment.
Option by option
A. Clonorchis sinensis (correct)
Correct. Raw fish, small operculated eggs and cholangiocarcinoma point to Clonorchis.
B. Fasciola hepatica
Fasciola hepatica is acquired from aquatic plants and has large eggs.
C. Schistosoma haematobium
Schistosoma haematobium causes bladder disease and squamous cell carcinoma of the bladder.
D. Paragonimus westermani
Paragonimus is a lung fluke acquired from raw crabs.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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