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Physiology · Cardiovascular: ECG in pre-excitation
Sample itemA 19-year-old with palpitations has an ECG showing a PR interval of 0.09 s with a slurred upstroke at the start of a broad QRS complex. Which mechanism explains the short PR interval?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. An accessory pathway bypasses the AV node, so the ventricle is activated early without the nodal delay
Normally the AV node delays conduction and gives a PR interval of 0.12 to 0.20 s. In Wolff-Parkinson-White syndrome an accessory pathway conducts to the ventricle without delay, producing a short PR and a slurred delta wave from early ventricular activation. The QRS widens because part of the ventricle is activated slowly through muscle.
Option by option
A. Early repolarisation of the atria
Atrial repolarisation is not a determinant of the PR interval.
B. Faster conduction through the AV node because of high sympathetic tone alone
Sympathetic tone shortens the PR slightly but does not give a delta wave.
C. An accessory pathway bypasses the AV node, so the ventricle is activated early without the nodal delay (correct)
Correct. Bypass of the nodal delay shortens the PR and produces the delta wave.
D. Delayed conduction in the His-Purkinje system
His-Purkinje delay would widen the QRS and not shorten the PR.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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