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Biochemistry · Enzymes
Sample itemWhat does a lower Km generally indicate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Higher substrate affinity
This item reviews Enzymes; Higher substrate affinity is the best answer because it directly matches the biochemical or pathological mechanism described.
Option by option
A. Lower enzyme amount
Lower enzyme amount does not fit the stated pattern.
B. No binding
No binding is plausible but not the best answer.
C. Higher Vmax always
Higher Vmax always is unsupported by the key feature.
D. Higher substrate affinity (correct)
Correct. Higher substrate affinity fits the defining mechanism.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.