Carbohydrate metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Carbohydrate metabolism

Sample item

What enzyme is deficient in classic galactosemia?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Galactose-1-phosphate uridyltransferase

The defining Carbohydrate metabolism relationship supports Galactose-1-phosphate uridyltransferase; it is the option that most directly explains the biochemical pathway or pathological process in the stem.

Option by option

  • A. Lactase

    Lactase does not match the stated carbohydrate metabolism mechanism.

  • B. Pyruvate carboxylase

    Pyruvate carboxylase does not account for the central finding in this item.

  • C. Hexokinase

    Hexokinase is relevant in a different context but is not supported here.

  • D. Galactose-1-phosphate uridyltransferase (correct)

    Correct. Galactose-1-phosphate uridyltransferase is the appropriate conclusion from the key feature.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is D, Galactose-1-phosphate uridyltransferase. The defining Carbohydrate metabolism relationship supports Galactose-1-phosphate uridyltransferase; it is the option that most directly explains the biochemical pathway or pathological process in the stem.

Why is "Lactase" not the answer?

Lactase does not match the stated carbohydrate metabolism mechanism.

Why is "Pyruvate carboxylase" not the answer?

Pyruvate carboxylase does not account for the central finding in this item.

Why is "Hexokinase" not the answer?

Hexokinase is relevant in a different context but is not supported here.

What concept does this question test?

It tests Carbohydrate metabolism in Biochemistry. The correct option holds because: Correct. Galactose-1-phosphate uridyltransferase is the appropriate conclusion from the key feature.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Carbohydrate metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.