Nucleotide metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Nucleotide metabolism

Sample item

What enzyme adds nucleotides during DNA replication?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. DNA polymerase

The defining Nucleotide metabolism relationship supports DNA polymerase; it is the option that most directly explains the biochemical pathway or pathological process in the stem.

Option by option

  • A. DNA polymerase (correct)

    Correct. DNA polymerase is the appropriate conclusion from the key feature.

  • B. Ligase only

    Ligase only is relevant in a different context but is not supported here.

  • C. RNA polymerase

    RNA polymerase does not match the stated nucleotide metabolism mechanism.

  • D. Topoisomerase only

    Topoisomerase only does not account for the central finding in this item.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is A, DNA polymerase. The defining Nucleotide metabolism relationship supports DNA polymerase; it is the option that most directly explains the biochemical pathway or pathological process in the stem.

Why is "Ligase only" not the answer?

Ligase only is relevant in a different context but is not supported here.

Why is "RNA polymerase" not the answer?

RNA polymerase does not match the stated nucleotide metabolism mechanism.

Why is "Topoisomerase only" not the answer?

Topoisomerase only does not account for the central finding in this item.

What concept does this question test?

It tests Nucleotide metabolism in Biochemistry. The correct option holds because: Correct. DNA polymerase is the appropriate conclusion from the key feature.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nucleotide metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.