Antihypertensives: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Antihypertensives

Sample item

What class blocks angiotensin II at its AT1 receptor?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Angiotensin receptor blocker

Angiotensin receptor blockers selectively antagonize AT1 receptors, reducing angiotensin II mediated vasoconstriction and aldosterone signaling.

Option by option

  • A. ACE inhibitor

    ACE inhibitors reduce angiotensin II formation upstream.

  • B. Angiotensin receptor blocker (correct)

    Correct: ARBs block the AT1 receptor.

  • C. Beta-2 agonist

    Beta-2 agonists promote bronchodilation rather than block AT1 receptors.

  • D. Thiazide diuretic

    Thiazides act in the distal convoluted tubule.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is B, Angiotensin receptor blocker. Angiotensin receptor blockers selectively antagonize AT1 receptors, reducing angiotensin II mediated vasoconstriction and aldosterone signaling.

Why is "ACE inhibitor" not the answer?

ACE inhibitors reduce angiotensin II formation upstream.

Why is "Beta-2 agonist" not the answer?

Beta-2 agonists promote bronchodilation rather than block AT1 receptors.

Why is "Thiazide diuretic" not the answer?

Thiazides act in the distal convoluted tubule.

What concept does this question test?

It tests Antihypertensives in Pharmacology. The correct option holds because: Correct: ARBs block the AT1 receptor.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antihypertensives?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.