Carbohydrate metabolism: practice question

The best answer is A, Thiamine pyrophosphate. Pyruvate dehydrogenase uses thiamine pyrophosphate among its cofactors to convert pyruvate into acetyl-CoA for entry into the citric acid cycle.

Biotin is used in carboxylation reactions.

Vitamin K is needed for clotting-factor carboxylation.

Ascorbate supports collagen hydroxylation and antioxidant functions.

It tests Carbohydrate metabolism in Biochemistry. The correct option holds because: Correct: thiamine pyrophosphate is required by pyruvate dehydrogenase.

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.