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Biochemistry · Heme metabolism
Sample itemWhat protein binds free hemoglobin in plasma after intravascular hemolysis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Haptoglobin
Haptoglobin binds free hemoglobin released into plasma, limiting oxidative injury and renal loss; levels may fall during intravascular hemolysis.
Option by option
A. Transferrin
Transferrin transports iron in plasma.
B. Albumin
Albumin maintains oncotic pressure and transports various molecules.
C. Haptoglobin (correct)
Correct: haptoglobin scavenges free plasma hemoglobin.
D. Ferritin
Ferritin stores intracellular iron.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.