Heme metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Heme metabolism

Sample item

What protein binds free hemoglobin in plasma after intravascular hemolysis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Haptoglobin

Haptoglobin binds free hemoglobin released into plasma, limiting oxidative injury and renal loss; levels may fall during intravascular hemolysis.

Option by option

  • A. Transferrin

    Transferrin transports iron in plasma.

  • B. Albumin

    Albumin maintains oncotic pressure and transports various molecules.

  • C. Haptoglobin (correct)

    Correct: haptoglobin scavenges free plasma hemoglobin.

  • D. Ferritin

    Ferritin stores intracellular iron.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is C, Haptoglobin. Haptoglobin binds free hemoglobin released into plasma, limiting oxidative injury and renal loss; levels may fall during intravascular hemolysis.

Why is "Transferrin" not the answer?

Transferrin transports iron in plasma.

Why is "Albumin" not the answer?

Albumin maintains oncotic pressure and transports various molecules.

Why is "Ferritin" not the answer?

Ferritin stores intracellular iron.

What concept does this question test?

It tests Heme metabolism in Biochemistry. The correct option holds because: Correct: haptoglobin scavenges free plasma hemoglobin.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Heme metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.