Local anesthetics: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Local anesthetics

Sample item

How do local anesthetics block nerve conduction?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Block voltage-gated sodium channels

Local anesthetics block voltage-gated sodium channels, preventing action-potential propagation along peripheral nerves and producing reversible regional anesthesia.

Option by option

  • A. Increase myelin growth

    Local anesthetics do not increase myelin growth.

  • B. Destroy acetylcholine

    Acetylcholine destruction is not their mechanism.

  • C. Activate potassium pumps

    Potassium pumps are not the local anesthetic target.

  • D. Block voltage-gated sodium channels (correct)

    Correct: sodium-channel blockade prevents nerve impulse conduction.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Anaesthesia questions

Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is D, Block voltage-gated sodium channels. Local anesthetics block voltage-gated sodium channels, preventing action-potential propagation along peripheral nerves and producing reversible regional anesthesia.

Why is "Increase myelin growth" not the answer?

Local anesthetics do not increase myelin growth.

Why is "Destroy acetylcholine" not the answer?

Acetylcholine destruction is not their mechanism.

Why is "Activate potassium pumps" not the answer?

Potassium pumps are not the local anesthetic target.

What concept does this question test?

It tests Local anesthetics in Anaesthesia. The correct option holds because: Correct: sodium-channel blockade prevents nerve impulse conduction.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Local anesthetics?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.