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Pharmacology · Diabetes drugs
Sample itemWhat is metformin's main glucose-lowering action?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Reduce hepatic glucose production
Metformin primarily reduces hepatic gluconeogenesis and improves insulin sensitivity, making it a foundational medication for many people with type 2 diabetes.
Option by option
A. Reduce hepatic glucose production (correct)
Correct: metformin lowers hepatic glucose output.
B. Destroy pancreatic beta cells
Metformin does not destroy beta cells.
C. Block insulin receptors
It improves rather than blocks insulin action.
D. Stimulate glucagon
Glucagon raises rather than lowers glucose.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.