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Forensic Medicine · Toxicology
Sample itemWhy can carbon monoxide poisoning be difficult to recognize from pulse oximetry alone?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Standard pulse oximeters may misread carboxyhaemoglobin as oxyhaemoglobin
Conventional pulse oximeters cannot reliably distinguish oxyhaemoglobin from carboxyhaemoglobin, so readings may appear falsely reassuring; co-oximetry and exposure history are important when carbon monoxide is suspected.
Option by option
A. Standard pulse oximeters may misread carboxyhaemoglobin as oxyhaemoglobin (correct)
Correct: standard oximetry can overestimate oxygenation in carbon monoxide poisoning.
B. It always produces severe cyanosis
Cyanosis may be absent despite dangerous poisoning.
C. Pulse oximetry measures only blood pressure
Pulse oximetry estimates oxygen saturation, not blood pressure.
D. Carbon monoxide never affects haemoglobin
Carbon monoxide binds haemoglobin strongly and impairs oxygen delivery.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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