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Physiology · Cardiovascular physiology
Sample itemWhich cardiac structure normally has the highest intrinsic pacemaker rate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Sinoatrial node
The sinoatrial node has the fastest spontaneous phase-4 depolarization and therefore normally sets heart rate; slower latent pacemakers can take over if SA-node activity or conduction fails.
Option by option
A. Atrioventricular node
AV node has a slower intrinsic escape rate.
B. Sinoatrial node (correct)
Correct: SA node normally dominates because it fires fastest.
C. Purkinje fibers
Purkinje fibers have the slowest of these intrinsic pacemaker rates.
D. Bundle of His
His bundle automaticity is slower than SA-node automaticity.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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