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Physiology · Neurophysiology
Sample itemWhich neurotransmitter is released at the skeletal neuromuscular junction?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Acetylcholine
Motor neurons release acetylcholine at the neuromuscular junction, where it activates nicotinic receptors on the muscle end plate and initiates a muscle action potential leading to contraction.
Option by option
A. Acetylcholine (correct)
Correct: acetylcholine mediates transmission at the skeletal neuromuscular junction.
B. Serotonin
Serotonin has central and gastrointestinal signaling roles.
C. Dopamine
Dopamine is important in central motor and reward pathways.
D. Gamma-aminobutyric acid
GABA is a major inhibitory neurotransmitter in the central nervous system.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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