Neurophysiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Neurophysiology

Sample item

Which neurotransmitter is released at the skeletal neuromuscular junction?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Acetylcholine

Motor neurons release acetylcholine at the neuromuscular junction, where it activates nicotinic receptors on the muscle end plate and initiates a muscle action potential leading to contraction.

Option by option

  • A. Acetylcholine (correct)

    Correct: acetylcholine mediates transmission at the skeletal neuromuscular junction.

  • B. Serotonin

    Serotonin has central and gastrointestinal signaling roles.

  • C. Dopamine

    Dopamine is important in central motor and reward pathways.

  • D. Gamma-aminobutyric acid

    GABA is a major inhibitory neurotransmitter in the central nervous system.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Physiology questions

Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is A, Acetylcholine. Motor neurons release acetylcholine at the neuromuscular junction, where it activates nicotinic receptors on the muscle end plate and initiates a muscle action potential leading to contraction.

Why is "Serotonin" not the answer?

Serotonin has central and gastrointestinal signaling roles.

Why is "Dopamine" not the answer?

Dopamine is important in central motor and reward pathways.

Why is "Gamma-aminobutyric acid" not the answer?

GABA is a major inhibitory neurotransmitter in the central nervous system.

What concept does this question test?

It tests Neurophysiology in Physiology. The correct option holds because: Correct: acetylcholine mediates transmission at the skeletal neuromuscular junction.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Neurophysiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.