Hormone biochemistry: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Hormone biochemistry

Sample item

Which receptor class is used by steroid hormones such as cortisol?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Intracellular receptor regulating gene transcription

Steroid hormones cross lipid membranes and bind intracellular receptors that alter transcription of target genes over a slower time course.

Option by option

  • A. Cell-surface tyrosine kinase only

    Tyrosine kinase receptors bind other hormone families.

  • B. Intracellular receptor regulating gene transcription (correct)

    Correct: steroid receptors act inside the cell on gene expression.

  • C. Ligand-gated ion channel only

    Ion channels mediate rapid membrane signalling.

  • D. Sodium channel receptor

    Sodium channels are not steroid hormone receptors.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is B, Intracellular receptor regulating gene transcription. Steroid hormones cross lipid membranes and bind intracellular receptors that alter transcription of target genes over a slower time course.

Why is "Cell-surface tyrosine kinase only" not the answer?

Tyrosine kinase receptors bind other hormone families.

Why is "Ligand-gated ion channel only" not the answer?

Ion channels mediate rapid membrane signalling.

Why is "Sodium channel receptor" not the answer?

Sodium channels are not steroid hormone receptors.

What concept does this question test?

It tests Hormone biochemistry in Biochemistry. The correct option holds because: Correct: steroid receptors act inside the cell on gene expression.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hormone biochemistry?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.