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Physiology · Respiratory physiology
Sample itemWhich factor shifts the oxyhaemoglobin dissociation curve to the right?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Increased carbon dioxide concentration
Higher carbon dioxide, temperature, and hydrogen ion concentration shift the curve right, promoting oxygen unloading to metabolically active tissues.
Option by option
A. Reduced hydrogen ion concentration
Lower hydrogen ion concentration means alkalosis and left shift.
B. Increased carbon dioxide concentration (correct)
Correct: carbon dioxide promotes the Bohr-effect right shift.
C. Fetal haemoglobin predominance
Fetal haemoglobin has higher oxygen affinity and shifts left.
D. Decreased temperature
Lower temperature shifts the curve left.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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