Gastrointestinal physiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Gastrointestinal physiology

Sample item

Which hormone stimulates pancreatic bicarbonate secretion after acid enters duodenum?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Secretin

Secretin is released by duodenal S cells in response to acid and stimulates bicarbonate-rich pancreatic secretion to neutralize luminal acidity.

Option by option

  • A. Gastrin

    Gastrin promotes gastric acid secretion.

  • B. Cholecystokinin

    Cholecystokinin stimulates enzyme secretion and gallbladder contraction.

  • C. Secretin (correct)

    Correct: secretin coordinates neutralization of duodenal acid.

  • D. Motilin

    Motilin coordinates fasting gastrointestinal motility.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is C, Secretin. Secretin is released by duodenal S cells in response to acid and stimulates bicarbonate-rich pancreatic secretion to neutralize luminal acidity.

Why is "Gastrin" not the answer?

Gastrin promotes gastric acid secretion.

Why is "Cholecystokinin" not the answer?

Cholecystokinin stimulates enzyme secretion and gallbladder contraction.

Why is "Motilin" not the answer?

Motilin coordinates fasting gastrointestinal motility.

What concept does this question test?

It tests Gastrointestinal physiology in Physiology. The correct option holds because: Correct: secretin coordinates neutralization of duodenal acid.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal physiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.