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Physiology · Reproductive physiology
Sample itemWhat triggers ovulation in a normal menstrual cycle?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Mid-cycle luteinizing hormone surge
A mid-cycle surge of luteinizing hormone triggers final oocyte maturation and rupture of the dominant follicle, releasing the ovum.
Option by option
A. Fall in follicle-stimulating hormone after menopause
Menopause does not represent the ovulatory cycle mechanism.
B. Mid-cycle luteinizing hormone surge (correct)
Correct: LH surge is the immediate ovulatory trigger.
C. Rise in prolactin during breastfeeding
Prolactin can suppress ovulation rather than trigger it.
D. Sustained progesterone peak before follicular growth
Progesterone rises mainly after ovulation from corpus luteum.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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