Blood physiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Blood physiology

Sample item

What is the main stimulus for erythropoietin secretion?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Reduced renal oxygen delivery

Renal peritubular cells increase erythropoietin production when oxygen delivery is reduced, stimulating bone marrow red-cell production.

Option by option

  • A. Elevated arterial oxygen content

    High oxygen content suppresses the hypoxic signal.

  • B. High plasma calcium concentration

    Calcium does not regulate erythropoietin production directly.

  • C. Reduced renal oxygen delivery (correct)

    Correct: tissue hypoxia drives erythropoietin secretion.

  • D. Increased gastric acid secretion

    Gastric acid has no role in erythropoietin control.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is C, Reduced renal oxygen delivery. Renal peritubular cells increase erythropoietin production when oxygen delivery is reduced, stimulating bone marrow red-cell production.

Why is "Elevated arterial oxygen content" not the answer?

High oxygen content suppresses the hypoxic signal.

Why is "High plasma calcium concentration" not the answer?

Calcium does not regulate erythropoietin production directly.

Why is "Increased gastric acid secretion" not the answer?

Gastric acid has no role in erythropoietin control.

What concept does this question test?

It tests Blood physiology in Physiology. The correct option holds because: Correct: tissue hypoxia drives erythropoietin secretion.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Blood physiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.