Endocrine physiology: thyroid hormones: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Endocrine physiology: thyroid hormones

Sample item

Thyroid hormone increases basal metabolic rate largely by increasing expression of what?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Na+/K+ ATPase

Thyroid hormones increase synthesis of Na+/K+ ATPase and many metabolic enzymes, increasing ATP turnover and oxygen consumption. This contributes to heat production.

Option by option

  • A. Epithelial sodium channel only

    ENaC is chiefly regulated by aldosterone.

  • B. Na+/K+ ATPase (correct)

    Correct. Increased Na+/K+ ATPase activity raises energy expenditure.

  • C. Aquaporin-2

    AQP2 is regulated by ADH in collecting duct.

  • D. H+/K+ ATPase in parietal cells

    Parietal-cell H+/K+ ATPase produces gastric acid.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is B, Na+/K+ ATPase. Thyroid hormones increase synthesis of Na+/K+ ATPase and many metabolic enzymes, increasing ATP turnover and oxygen consumption.

Why is "Epithelial sodium channel only" not the answer?

ENaC is chiefly regulated by aldosterone.

Why is "Aquaporin-2" not the answer?

AQP2 is regulated by ADH in collecting duct.

Why is "H+/K+ ATPase in parietal cells" not the answer?

Parietal-cell H+/K+ ATPase produces gastric acid.

What concept does this question test?

It tests Endocrine physiology: thyroid hormones in Physiology. This contributes to heat production.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Endocrine physiology: thyroid hormones?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.