Menopause: hormone therapy: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Menopause: hormone therapy

Sample item

For a patient with an intact uterus receiving systemic estrogen therapy for menopausal vasomotor symptoms, what additional hormone is generally required to protect the endometrium?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. A progestogen

Unopposed systemic estrogen can stimulate the endometrium and increase hyperplasia and cancer risk in people with a uterus. Adding an adequate progestogen provides endometrial protection.

Option by option

  • A. Testosterone only

    Testosterone does not provide standard endometrial protection.

  • B. A progestogen (correct)

    Correct. Progestogen opposes estrogenic endometrial proliferation.

  • C. Human chorionic gonadotropin

    hCG is a pregnancy hormone, not menopausal therapy.

  • D. Oxytocin

    Oxytocin contracts the uterus and has no role in menopausal endometrial protection.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this OBG question

What is the answer to this OBG question?

The best answer is B, A progestogen. Unopposed systemic estrogen can stimulate the endometrium and increase hyperplasia and cancer risk in people with a uterus.

Why is "Testosterone only" not the answer?

Testosterone does not provide standard endometrial protection.

Why is "Human chorionic gonadotropin" not the answer?

hCG is a pregnancy hormone, not menopausal therapy.

Why is "Oxytocin" not the answer?

Oxytocin contracts the uterus and has no role in menopausal endometrial protection.

What concept does this question test?

It tests Menopause: hormone therapy in OBG. Adding an adequate progestogen provides endometrial protection.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Menopause: hormone therapy?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.