Analgesia: NSAIDs: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Analgesia: NSAIDs

Sample item

Why might ketorolac be avoided in a patient with active gastrointestinal bleeding?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. It inhibits platelet cyclooxygenase and impairs aggregation

Ketorolac is a nonselective NSAID that inhibits platelet thromboxane production and can increase bleeding risk while also causing gastrointestinal and renal toxicity.

Option by option

  • A. It inhibits platelet cyclooxygenase and impairs aggregation (correct)

    Correct. Reduced thromboxane-mediated platelet function can worsen bleeding.

  • B. It antagonises opioid receptors

    NSAIDs do not antagonise opioid receptors.

  • C. It causes profound respiratory depression

    Respiratory depression is an opioid effect.

  • D. It blocks neuromuscular transmission

    Neuromuscular transmission is not its target.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is A, It inhibits platelet cyclooxygenase and impairs aggregation. Ketorolac is a nonselective NSAID that inhibits platelet thromboxane production and can increase bleeding risk while also causing gastrointestinal and renal toxicity.

Why is "It antagonises opioid receptors" not the answer?

NSAIDs do not antagonise opioid receptors.

Why is "It causes profound respiratory depression" not the answer?

Respiratory depression is an opioid effect.

Why is "It blocks neuromuscular transmission" not the answer?

Neuromuscular transmission is not its target.

What concept does this question test?

It tests Analgesia: NSAIDs in Anaesthesia. The correct option holds because: Correct. Reduced thromboxane-mediated platelet function can worsen bleeding.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Analgesia: NSAIDs?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.