Try it
Microbiology · Infection control
Sample itemWhy are alcohol hand rubs less effective against Clostridioides difficile spores?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Spores resist alcohol-based killing
C. difficile spores resist alcohol, so soap-and-water handwashing and environmental sporicidal cleaning are important in outbreak control.
Option by option
A. Spores are removed by gloves alone
Gloves complement but do not replace hand hygiene.
B. C. difficile is a virus
C. difficile is a spore-forming bacterium.
C. Spores resist alcohol-based killing (correct)
Correct: spores are not reliably killed by alcohol rub.
D. Alcohol increases spore germination only
Germination is not the reason for failure.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.