Antimicrobials: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Antimicrobials

Sample item

Why should aminoglycoside levels be monitored in prolonged therapy?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Nephrotoxicity and ototoxicity relate to exposure

Aminoglycosides have a narrow therapeutic window and accumulation can damage renal tubules and cochlear or vestibular hair cells.

Option by option

  • A. Nephrotoxicity and ototoxicity relate to exposure (correct)

    Correct: exposure-related renal and ear toxicity requires monitoring.

  • B. They cause universal neutropenia

    Neutropenia is not the classic major toxicity.

  • C. They always cause hypoglycaemia

    Hypoglycaemia is not their typical dose-limiting toxicity.

  • D. They are inactivated by stomach acid only

    Parenteral dosing bypasses gastric acid issue.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, Nephrotoxicity and ototoxicity relate to exposure. Aminoglycosides have a narrow therapeutic window and accumulation can damage renal tubules and cochlear or vestibular hair cells.

Why is "They cause universal neutropenia" not the answer?

Neutropenia is not the classic major toxicity.

Why is "They always cause hypoglycaemia" not the answer?

Hypoglycaemia is not their typical dose-limiting toxicity.

Why is "They are inactivated by stomach acid only" not the answer?

Parenteral dosing bypasses gastric acid issue.

What concept does this question test?

It tests Antimicrobials in Pharmacology. The correct option holds because: Correct: exposure-related renal and ear toxicity requires monitoring.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antimicrobials?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.