Endocrine drugs: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Endocrine drugs

Sample item

Which drug class can cause euglycaemic diabetic ketoacidosis?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. SGLT2 inhibitors

SGLT2 inhibitors increase urinary glucose loss and can rarely predispose to ketoacidosis with relatively normal glucose, especially during fasting or illness.

Option by option

  • A. SGLT2 inhibitors (correct)

    Correct: SGLT2 blockade is linked to euglycaemic ketoacidosis.

  • B. DPP-4 inhibitors only

    DPP-4 drugs do not have this characteristic association.

  • C. Thyroid hormone replacement

    Thyroid replacement has different risks.

  • D. Bisphosphonates

    Bisphosphonates act on bone resorption.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is A, SGLT2 inhibitors. SGLT2 inhibitors increase urinary glucose loss and can rarely predispose to ketoacidosis with relatively normal glucose, especially during fasting or illness.

Why is "DPP-4 inhibitors only" not the answer?

DPP-4 drugs do not have this characteristic association.

Why is "Thyroid hormone replacement" not the answer?

Thyroid replacement has different risks.

Why is "Bisphosphonates" not the answer?

Bisphosphonates act on bone resorption.

What concept does this question test?

It tests Endocrine drugs in Pharmacology. The correct option holds because: Correct: SGLT2 blockade is linked to euglycaemic ketoacidosis.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Endocrine drugs?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.