Carbohydrate metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Carbohydrate metabolism

Sample item

Which enzyme releases free glucose from glucose-6-phosphate in the fasting liver?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Glucose-6-phosphatase

Glucose-6-phosphatase in liver and kidney converts glucose-6-phosphate to free glucose, allowing hepatic glucose export during fasting.

Option by option

  • A. Pyruvate kinase

    Pyruvate kinase catalyses the final glycolytic step.

  • B. Lactate dehydrogenase

    Lactate dehydrogenase interconverts pyruvate and lactate.

  • C. Glucose-6-phosphatase (correct)

    Correct: this enzyme permits free glucose release into blood.

  • D. Phosphofructokinase-1

    PFK-1 drives a committed glycolytic step.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is C, Glucose-6-phosphatase. Glucose-6-phosphatase in liver and kidney converts glucose-6-phosphate to free glucose, allowing hepatic glucose export during fasting.

Why is "Pyruvate kinase" not the answer?

Pyruvate kinase catalyses the final glycolytic step.

Why is "Lactate dehydrogenase" not the answer?

Lactate dehydrogenase interconverts pyruvate and lactate.

Why is "Phosphofructokinase-1" not the answer?

PFK-1 drives a committed glycolytic step.

What concept does this question test?

It tests Carbohydrate metabolism in Biochemistry. The correct option holds because: Correct: this enzyme permits free glucose release into blood.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Carbohydrate metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.