Lipid metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Lipid metabolism

Sample item

What is the main source of ketone bodies during prolonged fasting?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Hepatic fatty-acid oxidation

The liver converts acetyl-CoA generated by fatty-acid oxidation into ketone bodies when carbohydrate availability and oxaloacetate are limited.

Option by option

  • A. Renal glucose reabsorption

    Kidney reabsorption does not make ketones.

  • B. Intestinal protein absorption

    Intestinal absorption is not the fasting source.

  • C. Hepatic fatty-acid oxidation (correct)

    Correct: liver fatty-acid oxidation supplies ketone precursors.

  • D. Muscle glycogen synthesis

    Muscle glycogen is not the main ketone source.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is C, Hepatic fatty-acid oxidation. The liver converts acetyl-CoA generated by fatty-acid oxidation into ketone bodies when carbohydrate availability and oxaloacetate are limited.

Why is "Renal glucose reabsorption" not the answer?

Kidney reabsorption does not make ketones.

Why is "Intestinal protein absorption" not the answer?

Intestinal absorption is not the fasting source.

Why is "Muscle glycogen synthesis" not the answer?

Muscle glycogen is not the main ketone source.

What concept does this question test?

It tests Lipid metabolism in Biochemistry. The correct option holds because: Correct: liver fatty-acid oxidation supplies ketone precursors.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Lipid metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.