Amino acids: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Amino acids

Sample item

Which amino acid is the biochemical precursor of nitric oxide in vascular endothelium?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Arginine

Nitric oxide synthase converts arginine to nitric oxide and citrulline; endothelial nitric oxide then promotes vascular smooth-muscle relaxation.

Option by option

  • A. Histidine

    Histidine is converted to histamine.

  • B. Methionine

    Methionine is important for methyl-group donation.

  • C. Tryptophan

    Tryptophan is a precursor of serotonin.

  • D. Arginine (correct)

    Correct: nitric oxide synthase uses arginine as substrate.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is D, Arginine. Nitric oxide synthase converts arginine to nitric oxide and citrulline; endothelial nitric oxide then promotes vascular smooth-muscle relaxation.

Why is "Histidine" not the answer?

Histidine is converted to histamine.

Why is "Methionine" not the answer?

Methionine is important for methyl-group donation.

Why is "Tryptophan" not the answer?

Tryptophan is a precursor of serotonin.

What concept does this question test?

It tests Amino acids in Biochemistry. The correct option holds because: Correct: nitric oxide synthase uses arginine as substrate.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Amino acids?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.