Gastrointestinal physiology: practice question

A Physiology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Physiology · Gastrointestinal physiology

Sample item

What triggers release of gastrin?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Peptides and gastric distension

Gastrin release from antral G cells is stimulated by peptides, amino acids, and gastric distension, promoting acid secretion and mucosal growth.

Option by option

  • A. Acid in duodenum only

    Duodenal acid chiefly stimulates secretin.

  • B. Bladder stretch

    Bladder stretch is unrelated.

  • C. Peptides and gastric distension (correct)

    Correct: food and distension stimulate gastrin.

  • D. High blood oxygen

    Oxygen does not regulate gastrin.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Physiology question

What is the answer to this Physiology question?

The best answer is C, Peptides and gastric distension. Gastrin release from antral G cells is stimulated by peptides, amino acids, and gastric distension, promoting acid secretion and mucosal growth.

Why is "Acid in duodenum only" not the answer?

Duodenal acid chiefly stimulates secretin.

Why is "Bladder stretch" not the answer?

Bladder stretch is unrelated.

Why is "High blood oxygen" not the answer?

Oxygen does not regulate gastrin.

What concept does this question test?

It tests Gastrointestinal physiology in Physiology. The correct option holds because: Correct: food and distension stimulate gastrin.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastrointestinal physiology?

For each system, sketch the key graph (pressure–volume loop, oxygen dissociation curve, nephron handling) and explain it aloud. Then use the flashcards and the other Physiology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.