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General Surgery · Pancreatic surgery: pancreatic cancer
Sample itemAn older patient has painless jaundice, weight loss, pale stools, dark urine, and a palpable nontender gallbladder. What diagnosis is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Carcinoma of the pancreatic head
A pancreatic-head malignancy can obstruct the distal bile duct, causing painless cholestatic jaundice and a distended nontender gallbladder. Cross-sectional imaging and tissue strategy are guided by specialist teams.
Option by option
A. Acute cholecystitis
Cholecystitis causes painful right-upper-quadrant inflammation.
B. Irritable bowel syndrome
IBS does not cause jaundice or weight loss.
C. Carcinoma of the pancreatic head (correct)
Correct. Painless obstructive jaundice with Courvoisier sign is concerning for pancreatic head cancer.
D. Viral hepatitis
Viral hepatitis causes hepatocellular rather than obstructive jaundice pattern.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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