Enzymology: competitive inhibition: practice question

The best answer is A, Km increases while Vmax remains unchanged. A competitive inhibitor competes with substrate at the active site, so more substrate is needed to reach half-maximal velocity.

Binding of inhibitor changes apparent substrate affinity.

This pattern is not characteristic of competitive inhibition.

Vmax is not increased by competitive inhibitors.

It tests Enzymology: competitive inhibition in Biochemistry. At sufficiently high substrate concentration, the same Vmax can still be reached.

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.